ICSI (Intracytoplasmic Sperm Injection) techniques involves the direct injection of a single sperm into each egg under direct microscopic vision. The introduction of ICSI has made it possible to fertilize eggs with sperm derived from men with the severest degrees of male infertility and in the process, to achieve pregnancy rates as high, if not higher than those that can be achieved through conventional IVF in non-male-factor cases.